In Alien Syndrome, players take control of the game's strong and enigmatic heroine – Earth Command Trooper Aileen Harding – and battle a variety of fearsome aliens and colossal bosses. Gamers choose from a wide selection of character specialties and skills as they progress through an engrossing campaign, protected by many different types of armor and using a variety of melee and ranged weaponry. Players can improve their heroine's statistics and discover a huge number of powerful new abilities as they fight through infested spaceships and bizarre alien planets.
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