There are 7 Bronze Trophies, 4 Silver Trophies, and 1 Gold Trophy.
|Lose any Story Mode level within 5 seconds||All Gummed Up|
|Get a combo-pop of 100 or more germs with one shot||Clean-a-rama|
|Complete a Story Mode level in under 30 seconds||Feverish Cleaning|
|Complete 20 different levels in a single run in Puzzle Mode||Germ-a-thon|
|Complete all Story Mode levels||Micro-Cleaner|
|Pop a germ of size 25x or greater||Mother of all Pops|
|Fire 50 germs in a single Story, Duel, or Arcade level||Oozie|
|Win the 15th round in a Duel match against "The Germinator"||Photo Finish|
|Complete all Puzzle Mode levels||Sound Logic|
|Collect all stars in Puzzle and Story Mode||The Germinator|
|Survive for 5 minutes or more in Arcade Mode||The Inoculator|
|Finish any Puzzle level with a single shot||The Marksman|
Contributed By: Guard Master.