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Complete each achievement to get the allotted gamerscore.

UnlockableHow to Unlock
Successfully invented all possible ammo types.Ammo Inventor (25)
Successfully invent at least 100 items.Avid Inventor (10)
Successfully invent at least one item.Basic Inventor (5)
The player has become a Big Daddy.Became a Big Daddy (30)
Purchase one slot in any Plasmid or Tonic track.Bought One Slot (5)
Beat the game on Hard difficulty without using a Vita Chamber.Brass Balls (100)
The player has broken Fontaine's mind control.Broke Fontaine's Mind Control (30)
The player has completed Sander Cohen's great masterpiece.Completed Cohen's Masterpiece (30)
Successfully complete the Welcome To Rapture Level.Completed Welcome (10)
Either Harvest or Rescue every Little Sister in the game.Dealt with every Little Sister (40)
The player has defeated Andrew Ryan.Defeated Andrew Ryan (30)
The player has defeated Atlas.Defeated Atlas (100)
The player has defeated the crazed Dr. Steinman.Defeated Dr. Steinman (15)
The player has defeated Peach Wilkins.Defeated Peach Wilkins (15)
Fully upgrade five weapons.Five Fully Upgraded Weapons (10)
The player has entered Sander Cohen's personal quarters.Found Cohen's Room (10)
Fully upgrade four weapons.Four Fully Upgraded Weapons (10)
Fully research the Bouncer.Fully Researched Bouncer (10)
Fully research the Leadhead Splicer.Fully Researched Gun Splicer (10)
Fully research the Houdini Splicer.Fully Researched Houdini Splicer (10)
Fully research the Little Sister.Fully Researched Little Sister (10)
Fully research the Nitro Splicer.Fully Researched Nitro Splicer (10)
Fully research the Rosie.Fully Researched Rosie (10)
Fully research the Spider Splicer.Fully Researched Spider Splicer (10)
Fully research the Thuggish Splicer.Fully Researched Thug Splicer (10)
Successfully hack a safe.Hacked a Safe (10)
Successfully hack a security bot.Hacked a Security Bot (10)
Successfully hack a security camera.Hacked a Security Camera (10)
Successfully hack a turret.Hacked a Turret (10)
Successfully hack a vending machine.Hacked a Vending Machine (10)
Find every audio diary.Historian (50)
The player has taken a picture of Sander Cohen's corpse.Irony (10)
Complete the game without harvesting any Little Sisters.Little Sister Savior (100)
Hit the jackpot at a slot machine.Lucky Winner (10)
Purchased every slot in all four Plasmid and Tonic tracks.Maxed All Tracks (50)
Purchased every slot in one of the Plasmid or Tonic tracks.Maxed One Track (20)
Fully upgrade one weapon.One Fully Upgraded Weapon (5)
Perform at least one successful hack.One Successful Hack (5)
Take at least one photo in every research group.Prolific Photographer (5)
Take a Research Photo of the highest grade.Quality Research Photo (20)
Max out all possible research.Research PhD (20)
Take at least one Research Photo of a Splicer.Researched a Splicer (5)
The player has restored the forests of Arcadia.Restored the Forest (15)
Complete the game on the hardest difficulty setting.Seriously Good At This (40)
Successfully complete 50 hacks.Skilled Hacker (40)
Fully upgrade three weapons.Three Fully Upgraded Weapons (10)
Shock an enemy in the water.Toaster in the Tub (10)
Collect or Invent 53 Tonics in the Physical, Engineering and Combat tracks.Tonic Collector (50)
Fully upgrade two weapons.Two Fully Upgraded Weapons (5)
Acquire at least one weapon upgrade.Upgraded a Weapon (5)
Acquire all upgrades for all weapons.Weapon Specialist (20)

Contributed By: Guard Master and Dre_Sizzle.

Alternate Ending

Depending on how you deal with the Little Sisters throughout the game, you will get a different ending.

UnlockableHow to Unlock
Save all the Little Sisters you encounter in the game.Ending A
Harvest all the Little Sisters you encounter in the game.Ending B
Harvest some of the Little Sisters in the game, and save the rest.Ending C (is very similar to Ending B but with a different tone)

Contributed By: horror_spooky and EddMario.